Mechanochemical synthesis of graphene oxide-supported transition metal catalysts for the oxidation of isoeugenol to vanillin

• Ana Franco,
• Sudipta De,
• Alina M. Balu,
• Araceli Garcia and
• Rafael Luque

Beilstein J. Org. Chem. 2017, 13, 1439–1445, doi:10.3762/bjoc.13.141

• ; isoeugenol; mechanochemical synthesis; non-enzymatic process; vanillin; Introduction Vanillin is the main flavor and aroma compound in vanilla. It is an aromatic compound (4-hydroxy-3-methoxybenzaldehyde) containing two reactive functional groups that are useful for the synthesis of thermoplastic polymers

Mechanistic investigations on six bacterial terpene cyclases

• Patrick Rabe,
• Thomas Schmitz and
• Jeroen S. Dickschat

Beilstein J. Org. Chem. 2016, 12, 1839–1850, doi:10.3762/bjoc.12.173

• ]. Their interconversion could be a non-enzymatic process catalysed by weak acids, e.g., during work-up, but the acid-catalysed conversion of 4a is known to give a mixture of α-, β-, and γ-eudesmol [57], but not 7-epi-α-eudesmol, which demonstrates the participation of the enzyme to fix 4a in the correct